17-HYDROXYPROGESTERONE ACETATE
3,20-Dioxopregn-4-en-17-beta-yl acetate
CAS: 17308-02-0
Molecular Formula: C23H32O4
17-HYDROXYPROGESTERONE ACETATE - Names and Identifiers
17-HYDROXYPROGESTERONE ACETATE - Physico-chemical Properties
| Molecular Formula | C23H32O4 |
| Molar Mass | 372.51 |
| Density | 1.14±0.1 g/cm3(Predicted) |
| Melting Point | 198 °C |
| Boling Point | 490.2±45.0 °C(Predicted) |
| Storage Condition | 2-8℃ |
| Physical and Chemical Properties | Chemical properties crystallization (acetone). Melting point 246.5 ℃. |
| Use | Use an intermediate of megestrol. |
17-HYDROXYPROGESTERONE ACETATE - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R40 - Limited evidence of a carcinogenic effect R48 - Danger of serious damage to health by prolonged exposure |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2811 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | TU5074000 |
17-HYDROXYPROGESTERONE ACETATE - Upstream Downstream Industry
| Raw Materials | 16a,17a-Epoxyprogesterone Hydroxyprogesterone |
17-HYDROXYPROGESTERONE ACETATE - Production method
16, 17α-epoxypregnan-4-ene-3, 20-dione (I. e. epoxyprogesterone) can be used by (on the epoxy group) hydrogen bromide addition and catalytic hydrogenation (removal of 16-position Bromine) to generate 17 α-hydroxypregnan-4-ene-3, 20-dione (ie 17 α-hydroxyprogesterone), the product was then prepared by (3-position, 17-position hydroxyl) acetylation and partial hydrolysis (3-position ketone and 4-position double bond restoration).
Last Update：2024-04-09 21:01:54
17-HYDROXYPROGESTERONE ACETATE - Reference Information
| chemical properties | crystallization (acetone). Melting point 246.5 ℃. |
| use | intermediate of medroxyprogesterone. |
| production method | 16,17 α-epoxyprogesterone -4-ene -3 can be used, 20-diketone (I. e. epoxyprogesterone) is added by hydrogen bromide (on the epoxy group), and catalytic hydrogenation (removal of 16-position bromine) to generate 17 α-hydroxygestroster-4-ene-3, 20-Dione (ie 17 α-hydroxyprogesterone), the product was then acetylated (3-position, 17-position hydroxyl) and partially hydrolyzed (3-position ketone group and 4-position double bond recovery). |
Last Update：2024-04-09 21:04:16
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CAS: 17308-02-0
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Product Name: 17-Hydroxypregn-4-ene-3,20-dione acetate Visit Supplier Webpage Request for quotation
CAS: 17308-02-0
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CAS: 17308-02-0
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Raw Materials for 17-HYDROXYPROGESTERONE ACETATE